The intention of the trial is to rigorously test, using a high level of scientific scrutiny, the use of decompressive surgery for central spinal canal stenosis.
The SUcceSS trial aims to randomly allocate participants with chronic, symptomatic lumbar spinal stenosis to either decompressive surgery or placebo surgery to measure the efficacy of decompressive surgery on patients with central spinal canal stenosis. Decompressive spinal surgery via laminectomy for symptomatic spinal stenosis is justified primarily upon clinical experience, expert consensus and pathophysiological considerations. The efficacy of surgical decompression, the most popular procedure for spinal stenosis, has not yet been proven. There is an urgent requirement to test decompressive surgery for spinal stenosis as the intervention is expensive and potentially harmful and is increasingly used due to our ageing population.
This study is currently recruiting. You may be eligible to participate if you are aged 50 years or older and have experienced pain, numbness and/or fatigue below the gluteal line with or without back pain (if back pain present, leg pain is greater than back pain) that is precipitated by walking and alleviated by sitting or lumbar flexion.
Principal Investigator: Associate Professor Manuela Ferreira
Institute for Musculoskeletal Health Investigators: Professor Ian Harris, Professor Jane Latimer, Professor Chris Maher
This trial has been granted ethics approval by the South Eastern Sydney Local Health District Ethics, and funding from the NHMRC. For further information about this Institute for Bone and Joint Research trial, please contact Associate Professor Manuela Ferreira.